Platelet-rich plasma (PRP) therapy has become one of the most widely used adjunctive treatments in hair restoration. Understanding the evidence, the procedure, and realistic expectations helps patients make informed decisions.
What Is PRP?
PRP is derived from the patient's own blood. A blood sample is taken (typically 20–60 ml) and centrifuged to separate the plasma from red blood cells and other components. The resulting platelet-rich plasma contains a concentrated level of growth factors — proteins that stimulate cellular activity, blood vessel formation, and tissue repair.
When injected into the scalp, these growth factors stimulate hair follicle activity, improve circulation in the scalp, and may prolong the anagen (growth) phase of the hair cycle.
What Does the Evidence Say?
Multiple randomised controlled trials and systematic reviews have demonstrated that PRP therapy produces statistically significant improvements in hair density and follicle count in androgenetic alopecia patients compared to control groups. The quality of evidence has improved considerably since 2015.
Key points from the evidence:
- Consistent improvements in hair density at 3 and 6 months
- Effects appear to be maintained with repeat sessions
- More pronounced effects in early to moderate hair loss than advanced cases
- Evidence for female pattern hair loss also positive, though less extensive than for male pattern
PRP Limitations
PRP is not a cure for hair loss and does not stop DHT-mediated follicle miniaturisation the way finasteride does. The effects are supportive rather than disease-modifying. Results vary between patients, and not everyone responds equally.
PRP Protocol: How Many Sessions?
Typical protocol:
- Initial course: 3 sessions at monthly intervals
- Maintenance: 1–2 sessions annually
The initial course produces the most significant results. Maintenance sessions sustain the benefit.
PRP with Hair Transplant: The Combination Approach
PRP is frequently used alongside hair transplantation. Applications include:
Soaking extracted grafts in PRP before implantation — some evidence suggests this may improve graft survival rates.
Injecting PRP into recipient zone on the day of transplant or shortly after — may reduce shock loss and support early graft establishment.
Post-transplant sessions at months 1, 3, and 6 — supports overall scalp health and reduces native hair shock loss.
Is PRP Worth It?
For patients with mild to moderate hair loss who want to support their medical regimen and delay or reduce the scope of eventual transplantation, PRP is a reasonable addition. The evidence is positive, the procedure is safe (autologous — uses the patient's own blood), and side effects are minimal.
For patients seeking a substitute for finasteride or minoxidil — PRP alone is not sufficient. The combination of medical therapy and PRP is more effective than either alone.
Interested in PRP as part of your hair treatment plan? Our team will advise on the most appropriate protocol for your specific situation.